Arterial spin labeling of cerebral perfusion territories using a separate labeling coil.
J Magn Reson Imaging
; 27(5): 970-7, 2008 May.
Article
em En
| MEDLINE
| ID: mdl-18425844
ABSTRACT
PURPOSE:
To obtain cerebral perfusion territories of the left, the right, and the posterior circulation in humans with high signal-to-noise ratio (SNR) and robust delineation. MATERIALS ANDMETHODS:
Continuous arterial spin labeling (CASL) was implemented using a dedicated radio frequency (RF) coil, positioned over the neck, to label the major cerebral feeding arteries in humans. Selective labeling was achieved by flow-driven adiabatic fast passage and by tilting the longitudinal labeling gradient about the Y-axis by theta = +/- 60 degrees .RESULTS:
Mean cerebral blood flow (CBF) values in gray matter (GM) and white matter (WM) were 74 +/- 13 mL . 100 g(-1) . minute(-1) and 14 +/- 13 mL . 100 g(-1) . minute(-1), respectively (N = 14). There were no signal differences between left and right hemispheres when theta = 0 degrees (P > 0.19), indicating efficient labeling of both hemispheres. When theta = +60 degrees , the signal in GM on the left hemisphere, 0.07 +/- 0.06%, was 92% lower than on the right hemisphere, 0.85 +/- 0.30% (P < 1 x 10(-9)), while for theta = -60 degrees , the signal in the right hemisphere, 0.16 +/- 0.13%, was 82% lower than on the contralateral side, 0.89 +/- 0.22% (P < 1 x 10(-10)). Similar attenuations were obtained in WM.CONCLUSION:
Clear delineation of the left and right cerebral perfusion territories was obtained, allowing discrimination of the anterior and posterior circulation in each hemisphere.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Marcadores de Spin
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Artérias Cerebrais
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Circulação Cerebrovascular
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Angiografia por Ressonância Magnética
Limite:
Adult
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Female
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Humans
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Male
Idioma:
En
Revista:
J Magn Reson Imaging
Assunto da revista:
DIAGNOSTICO POR IMAGEM
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Estados Unidos