A molecular clutch disables flagella in the Bacillus subtilis biofilm.
Science
; 320(5883): 1636-8, 2008 Jun 20.
Article
em En
| MEDLINE
| ID: mdl-18566286
ABSTRACT
Biofilms are multicellular aggregates of sessile bacteria encased by an extracellular matrix and are important medically as a source of drug-resistant microbes. In Bacillus subtilis, we found that an operon required for biofilm matrix biosynthesis also encoded an inhibitor of motility, EpsE. EpsE arrested flagellar rotation in a manner similar to that of a clutch, by disengaging motor force-generating elements in cells embedded in the biofilm matrix. The clutch is a simple, rapid, and potentially reversible form of motility control.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Bacillus subtilis
/
Proteínas de Bactérias
/
Biofilmes
/
Proteínas Motores Moleculares
/
Flagelos
Idioma:
En
Revista:
Science
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Estados Unidos