Bone alterations during HIV infection.
New Microbiol
; 31(2): 155-64, 2008 Apr.
Article
em En
| MEDLINE
| ID: mdl-18623979
ABSTRACT
Osteopenia and osteoporosis are common in HIV-1-infected individuals and represent a challenge in clinical and therapeutic management. Since the mechanisms underlying this degenerative process are largely unsettled and it has not yet been determined whether bone dysfunction is linked to HIV-1-mediated direct and/or indirect effects on osteoblasts/osteoclasts cross-talk regulation, this brief review analyzes an array of mechanisms that could account for the dramatic bone derangement (bone loss and osteopenia/osteoporosis) during the course of HIV-1 infection.
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Base de dados:
MEDLINE
Assunto principal:
Osteoporose
/
Doenças Ósseas Metabólicas
/
Infecções por HIV
Limite:
Adult
/
Child
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
New Microbiol
Assunto da revista:
MICROBIOLOGIA
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Itália