[Electrochemical behaviour of the adriamycin on the cobalt nanoparticles modified ITO electrode].
Yao Xue Xue Bao
; 43(3): 303-7, 2008 Mar.
Article
em Zh
| MEDLINE
| ID: mdl-18630269
ABSTRACT
A cobalt nanoparticles modified ITO electrode (NpCo/ITO) was prepared by casting cobalt nanoparticles onto ITO electrode and the cobalt nanoparticles were synthesized by NaHB4 reduction. The electrochemical behaviors of adriamycin (ADM) on NpCo/ITO were studied. The modified ITO electrode was characterized by cyclic voltammetry (CV), scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS). In a 0.01 mol L(-1) PBS (pH 8.0) buffer solution, a sensitive reduction peak of ADM was obtained. A linear relationship is held between the peak current and ADM concentration in the range of 1.0 x 10(-8) - 2.0 x 10(-6) mol L(-1) with detection of 5.0 x 10(-9) mol L(-1)- by cyclic voltammetry (CV) response. The reduction process was irreversible with adsorption at the NpCo/ITO electrode. The modified electrode showed an excellent electrocatalytic activity for the ADM electrochemical reduction.
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Base de dados:
MEDLINE
Assunto principal:
Doxorrubicina
/
Cobalto
/
Eletrodos
/
Nanopartículas
/
Antineoplásicos
Tipo de estudo:
Diagnostic_studies
Idioma:
Zh
Revista:
Yao Xue Xue Bao
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
China