Fatal injection of ranitidine: a case report.
J Med Case Rep
; 2: 232, 2008 Jul 17.
Article
em En
| MEDLINE
| ID: mdl-18637187
ABSTRACT
INTRODUCTION:
Ranitidine hydrochloride (Zantac), a histamine-2-receptor antagonist, is a widely used medication with an excellent safety record. Anaphylactic reaction to ranitidine is an extremely rare event and a related death has never been described in the literature. CASE PRESENTATION We present the clinical history, histological and toxicological data of a 51-year-old man with negative anamnesis for allergic events, who died suddenly after the intravenous administration of one phial of Zantac 50 mg prescribed as a routine post-surgical prophylaxis for stress ulcer.CONCLUSION:
Although the incidence of anaphylactic reactions related to ranitidine is low, caution needs to be exercised on administration of this drug. In addition, further study is needed to define strategies for the prevention of adverse drug reactions in hospitalized patients.
Texto completo:
1
Base de dados:
MEDLINE
Idioma:
En
Revista:
J Med Case Rep
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Itália