The anemia of ageing is not associated with increased plasma hepcidin levels.
Blood Cells Mol Dis
; 41(3): 252-4, 2008.
Article
em En
| MEDLINE
| ID: mdl-18676162
ABSTRACT
It has been proposed that the anemia of ageing may be caused, at least in part, by elevated hepcidin levels, representing a response to increased IL-6 levels. Using a recently developed immunoassay, we have measured the plasma hepcidin levels of eight patients with the anemia of ageing and sex- and age-matched controls, and found that the levels of hepcidin were not increased in patients with the anemia of ageing. In contrast, patients with the anemia of inflammation have higher hepcidin levels than sex- and age-matched controls. In the overall group there was a strong correlation between serum ferritin levels and hepcidin levels, as has been found previously.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Envelhecimento
/
Peptídeos Catiônicos Antimicrobianos
/
Anemia
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Blood Cells Mol Dis
Assunto da revista:
HEMATOLOGIA
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Estados Unidos