Dust and chemical exposures, and miscarriage risk among women textile workers in Shanghai, China.
Occup Environ Med
; 66(3): 161-8, 2009 Mar.
Article
em En
| MEDLINE
| ID: mdl-18805889
ABSTRACT
INTRODUCTION:
To investigate possible associations between miscarriage and occupational exposures in the Shanghai textile industry.METHODS:
A retrospective cohort study of miscarriages among 1752 women in the Shanghai textile industry was conducted. Reproductive history was self-reported by women and occupational work histories were collected from factory personnel records. Occupational exposures were assigned by linking work history information to an industry-specific job-exposure matrix informed by factory-specific textile process information and industrial hygiene assessments. Estimates of cotton dust and endotoxin exposure were also assigned. Odds ratios (OR) and 95% CI were estimated by multivariate logistic regression, with adjustment for age at pregnancy, educational level, smoking status of the woman and her spouse, use of alcohol, and woman's year of birth.RESULTS:
An elevation in risk of a spontaneously aborted first pregnancy was associated with exposure to synthetic fibres (OR 1.89, 95% CI 1.20 to 3.00) and mixed synthetic and natural fibres (OR 3.31, 95% CI 1.30 to 8.42). No increased risks were observed for women working with solvents, nor were significant associations observed with quantitative cotton dust or endotoxin exposures. Associations were robust and similar when all pregnancies in a woman's reproductive history were considered.CONCLUSIONS:
Occupational exposure to synthetic fibres may cause miscarriages, and this possibility should be the subject of further investigation.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Indústria Têxtil
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Aborto Espontâneo
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Poluentes Ocupacionais do Ar
/
Poeira
/
Doenças Profissionais
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Adult
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Aged
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Female
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Humans
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Middle aged
/
Pregnancy
País/Região como assunto:
Asia
Idioma:
En
Revista:
Occup Environ Med
Assunto da revista:
MEDICINA OCUPACIONAL
/
SAUDE AMBIENTAL
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
Estados Unidos