Bone marrow biopsies in patients 85 years or older.
Am J Clin Pathol
; 130(5): 832-5, 2008 Nov.
Article
em En
| MEDLINE
| ID: mdl-18854278
ABSTRACT
Increasing numbers of bone marrow aspirates and core biopsies are done in very elderly people; there is little published literature regarding the usefulness of bone marrow biopsies in these patients. We undertook a retrospective review of 119 bone marrow aspirates and biopsies from patients 85 years or older. These procedures were performed for a variety of abnormalities, including unexplained cytopenias; evaluation of a known myelodysplastic syndrome; suspicion or follow-up of plasma cell myeloma, thrombocytosis, or leukocytosis; and suspicion or staging of lymphoma. When staging or follow-up biopsies were excluded, 34 (43%) of 79 yielded specific diagnoses. Follow-up was available for 45 patients, and of these 45, 20 patients received therapy 17 were treated with an abbreviated or modified regimen, and 12 were treated for leukemia/lymphoma. Therapy failed in all patients. As a result of these biopsies, relatively few patients received more than supportive treatment, suggesting that higher thresholds for biopsy for cytopenias may be indicated.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Biópsia
/
Exame de Medula Óssea
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
Limite:
Aged80
/
Humans
Idioma:
En
Revista:
Am J Clin Pathol
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Estados Unidos