Control of ColE1 plasmid replication by antisense RNA.
Trends Genet
; 7(7): 230-5, 1991 Jul.
Article
em En
| MEDLINE
| ID: mdl-1887504
ABSTRACT
One of the two major classes of regulatory strategies that control plasmid copy number involves recognition via base pairing between two plasmid-encoded complementary RNAs. The detailed analysis of this control circuitry has revealed some features of regulatory mechanisms based on RNA-RNA interaction that distinguish them from those based on protein-nucleic acid interaction. These features provide a framework with which to understand other regulatory mechanisms based on RNA-RNA interaction, and will aid in the design of efficient artificial antisense RNA systems.
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Base de dados:
MEDLINE
Assunto principal:
RNA Antissenso
/
Proteínas de Ligação a RNA
/
Plasmídeos de Bacteriocinas
/
Replicação do DNA
Idioma:
En
Revista:
Trends Genet
Assunto da revista:
GENETICA
Ano de publicação:
1991
Tipo de documento:
Article
País de afiliação:
Itália