Mitochondrial energetic metabolism: a simplified model of TCA cycle with ATP production.
J Theor Biol
; 258(3): 455-64, 2009 Jun 07.
Article
em En
| MEDLINE
| ID: mdl-19007794
ABSTRACT
Mitochondria play a central role in cellular energetic metabolism. The essential parts of this metabolism are the tricarboxylic acid (TCA) cycle, the respiratory chain and the adenosine triphosphate (ATP) synthesis machinery. Here a simplified model of these three metabolic components with a limited set of differential equations is presented. The existence of a steady state is demonstrated and results of numerical simulations are presented. The relevance of a simple model to represent actual in vivo behavior is discussed.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Simulação por Computador
/
Trifosfato de Adenosina
/
Ciclo do Ácido Cítrico
/
Mitocôndrias
Limite:
Animals
/
Humans
Idioma:
En
Revista:
J Theor Biol
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
França