Hypogammaglobulinemia and infection risk in solid organ transplant recipients.
Curr Opin Organ Transplant
; 13(6): 581-5, 2008 Dec.
Article
em En
| MEDLINE
| ID: mdl-19060546
ABSTRACT
PURPOSE OF REVIEW Hypogammaglobulinemia may develop as a result of a number of immune deficiency syndromes that can be devastating. This review article explores the risk of infection associated with hypogammaglobulinemia in solid organ transplantation and discusses therapeutic strategies to alleviate such a risk. RECENT FINDINGS:
Hypogammaglobulinemia is associated with increased risk of opportunistic infections, particularly during the 6-month posttransplant period when viral infections are most prevalent. The preemptive use of immunoglobulin replacement results in a significant reduction of opportunistic infections in patients with moderate and severe hypogammaglobulinemia.SUMMARY:
Monitoring immunoglobulin G levels may aid in clinical management of solid organ transplant recipients. The preemptive use of immunoglobulin replacement may serve as a new strategy for managing solid organ transplant recipients with hypogammaglobulinemia.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Infecções Oportunistas
/
Doenças Transmissíveis
/
Transplante de Órgãos
/
Agamaglobulinemia
Tipo de estudo:
Etiology_studies
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Curr Opin Organ Transplant
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Estados Unidos