[Investigation of triazavirin antiviral activity against influenza A virus (H5N1) in cell culture].

Loginova, S Ia; Borisevich, S V; Maksimov, V A; Bondarev, V P; Kotovskaia, S K; Rusinov, V L; Charushin, V N

Loginova, S Ia; Borisevich, S V; Maksimov, V A; Bondarev, V P; Kotovskaia, S K; Rusinov, V L; Charushin, V N.

Antibiot Khimioter ; 52(11-12): 18-20, 2007.

Article em Ru | MEDLINE | ID: mdl-19275052

ABSTRACT

ABSTRACT

Analysis of triazavirin efficacy with respect to influenza A virus (H5N1) in sensitive cell culture MDSK vs. effective antigrippe drugs, such as tamiflu, remantadin and arbidol showed that triazavirin in a wide range of the concentrations was efficient in inhibition of the virus cytopathic activity and formation of the specific hemagglutinin.

Assuntos

Antivirais/farmacologia; Azóis/farmacologia; Virus da Influenza A Subtipo H5N1/efeitos dos fármacos; Triazinas/farmacologia; Animais; Linhagem Celular; Cães; Hemaglutininas Virais/biossíntese; Triazóis

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Base de dados: MEDLINE Assunto principal: Antivirais / Azóis / Triazinas / Virus da Influenza A Subtipo H5N1 Limite: Animals Idioma: Ru Revista: Antibiot Khimioter Assunto da revista: TERAPIA POR MEDICAMENTOS Ano de publicação: 2007 Tipo de documento: Article

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