Chest wall reconstruction with degradable processed sheep dermal collagen in dogs.
Ann Thorac Surg
; 52(4): 821-5, 1991 Oct.
Article
em En
| MEDLINE
| ID: mdl-1929636
ABSTRACT
Chest wall defects resulting from oncological operations often require prosthetic repair. The objectives of prosthetic repair are to provide a cosmetically acceptable substitute, prevent paradoxical chest wall movement, and protect vital organs. Of the many materials that have been used in these repairs, none have proved to be ideal. The aim of our study was to investigate the application of a biodegradable material--processed sheep dermal collagen--as a chest wall prosthesis. A full-thickness chest wall defect of 10 x 10 cm was created in 12 dogs; 10 had repair with a processed sheep dermal collagen prosthesis and 2, the controls, with polypropylene mesh. In this study, the biomaterial fulfilled its function as a chest wall prosthesis at 24 weeks' follow-up. No respiratory problems were seen, the chest wall remained stable with minimal and decreasing respiratory paradoxical movement, and the processed sheep dermal collagen slowly degraded and was replaced by the host collagen. Processed sheep dermal collagen offers long-term advantages because it is degradable. Late complications from a nonabsorbable prosthesis, ie, infection or disintegration of the material possibly causing extrusion or fistula formation, are avoided.
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Base de dados:
MEDLINE
Assunto principal:
Próteses e Implantes
/
Cirurgia Torácica
/
Materiais Biocompatíveis
/
Colágeno
Limite:
Animals
Idioma:
En
Revista:
Ann Thorac Surg
Ano de publicação:
1991
Tipo de documento:
Article
País de afiliação:
Holanda