[Change of nitric oxide metabolites in patients with chronic pancreatitis].
Eksp Klin Gastroenterol
; (7): 33-7, 2008.
Article
em Ru
| MEDLINE
| ID: mdl-19334442
ABSTRACT
72 patients with chronic pancreatitis were investigated. The levels of nitrogen oxide in the blood and urine were examined in the patients with chronic pancreatitis depend on the disease's stage and its complications. The nitrogen oxide metabolites were determined to all patients (by method of V. A. Metelskaya, 2005) The trustworthy differences of NO levels were revealed depend on the chronic pancreatitis complications presence. The patients with the pancreatic hypertension due to pancreatic calcinosis, that was accompanied persistent painful syndrome and relativelly high blood amylase level (amylase increase 3-4 times in comparison with its normal level) were demonstrated the high NO levels. The tendency to the lowering of level NO and painful syndrome with blood amylase activity reduce were revealed in the patients with surgical treatment of the complicated chronic pancreatitis. The lowering of the painful syndrome and the blood amylase activity follow to normalisaton of pancreatic juice outflow and reduce of the inflammation in parenchyma pancreas. So, the revealed connection increase of NO level and pancreatic inflammation may be the additional criterions for the surgical treatment of such patients.
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Base de dados:
MEDLINE
Assunto principal:
Pancreatite Crônica
/
Óxido Nítrico
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Ru
Revista:
Eksp Klin Gastroenterol
Assunto da revista:
GASTROENTEROLOGIA
Ano de publicação:
2008
Tipo de documento:
Article