Models of astrocytic Ca dynamics and epilepsy.
Drug Discov Today Dis Models
; 5(1): 13-18, 2008.
Article
em En
| MEDLINE
| ID: mdl-19343094
ABSTRACT
Neurons have been the focus of neuroscience research. Only recently, however, astrocytes, a subset of glial cells, have been on the neurobiology "radar" owing to their Ca(2+) excitability, which allows them to signal to other astrocytes and neurons. This review summarizes the models for studying astrocytic Ca(2+) dynamics and the consequential Ca(2+)- dependent glutamate release, which plays a role in astrocytic-neuronal signaling and have been implicated in epilepsy.
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MEDLINE
Idioma:
En
Revista:
Drug Discov Today Dis Models
Ano de publicação:
2008
Tipo de documento:
Article