[Language development impairment and trisomy 8 mosaicism]. / Sprachentwicklungsstörung bei Mosaik-Trisomie 8.
HNO
; 57(7): 685-9, 2009 Jul.
Article
em De
| MEDLINE
| ID: mdl-19547944
ABSTRACT
Constitutional trisomy 8 mosaicism (46,XX/47,XX,+8 or 46,XY/47,XY,+8) is characterized by trisomic distribution of chromosomes in some but not all cells of the body. The full condition presents with physical stigmata, skeletal abnormalities and a mild to moderate cognitive impairment.Here we present a boy aged 3 years 10 months with partial trisomy 8 who was referred because of a language impairment. Because of known anomalies (corpus callous agenesis, deformities of the spine) a chromosomal analysis was initiated.This case highlights the necessity for an interdisciplinary diagnostic approach in children with language impairment and other constitutional disorders.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Trissomia
/
Síndromes Mielodisplásicas
/
Cromossomos Humanos Par 8
/
Transtornos da Linguagem
Limite:
Child, preschool
/
Humans
/
Male
Idioma:
De
Revista:
HNO
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
Alemanha