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Chemical validation of trypanothione synthetase: a potential drug target for human trypanosomiasis.
Torrie, Leah S; Wyllie, Susan; Spinks, Daniel; Oza, Sandra L; Thompson, Stephen; Harrison, Justin R; Gilbert, Ian H; Wyatt, Paul G; Fairlamb, Alan H; Frearson, Julie A.
Afiliação
  • Torrie LS; Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, United Kingdom.
  • Wyllie S; Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, United Kingdom.
  • Spinks D; Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, United Kingdom.
  • Oza SL; Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, United Kingdom.
  • Thompson S; Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, United Kingdom.
  • Harrison JR; Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, United Kingdom.
  • Gilbert IH; Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, United Kingdom.
  • Wyatt PG; Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, United Kingdom.
  • Fairlamb AH; Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, United Kingdom.
  • Frearson JA; Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, United Kingdom. Electronic address: j.a.frearson@dundee.ac.uk.
J Biol Chem ; 284(52): 36137-36145, 2009 Dec 25.
Article em En | MEDLINE | ID: mdl-19828449
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Trypanosoma brucei brucei / Tripanossomíase Africana / Proteínas de Protozoários / Amida Sintases / Inibidores Enzimáticos / Antiprotozoários Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2009 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Trypanosoma brucei brucei / Tripanossomíase Africana / Proteínas de Protozoários / Amida Sintases / Inibidores Enzimáticos / Antiprotozoários Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2009 Tipo de documento: Article País de afiliação: Reino Unido