NDP52: the missing link between ubiquitinated bacteria and autophagy.
Nat Immunol
; 10(11): 1137-9, 2009 Nov.
Article
em En
| MEDLINE
| ID: mdl-19841643
Mammalian cells ubiquitinate bacteria that erroneously enter the cytosol and target these intruding microbes for destruction by autophagy. New work shows that the protein NDP52 directly binds to ubiquitinated bacteria and facilitates the assembly of an autophagic membrane that surrounds these invaders.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Autofagia
/
Proteínas Nucleares
/
Salmonella enterica
/
Ubiquitina
Limite:
Humans
Idioma:
En
Revista:
Nat Immunol
Assunto da revista:
ALERGIA E IMUNOLOGIA
Ano de publicação:
2009
Tipo de documento:
Article