Determination of methylene blue residues in aquatic products by liquid chromatography-tandem mass spectrometry.
J Sep Sci
; 32(23-24): 4193-9, 2009 Dec.
Article
em En
| MEDLINE
| ID: mdl-20066681
ABSTRACT
A method for the determination and confirmation of methylene blue (MB) in aquatic products was developed. Residues of MB were extracted from homogenized tissues with acetonitrile/sodium acetate buffer solution, and simply cleaned up with dichloromethane liquid/liquid extraction. After concentration and dissolution, the sample solutions were cleaned up by the neutral alumina and weak cation-exchange solid phase extraction (SPE) cartridge, prior to LC-MS/MS analysis. MB was determined at 1.0-20 microg/kg in eel, toasted eel and shrimp, with a limit of quantification of 0.5 microg/kg. Recovery for MB was between 73.0% and 108.3%. This method is fast, exact and sensitive. It can be applied to determine MB in aquatic products.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Poluentes Químicos da Água
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Cromatografia Líquida de Alta Pressão
/
Espectrometria de Massas em Tandem
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Azul de Metileno
Limite:
Animals
Idioma:
En
Revista:
J Sep Sci
Ano de publicação:
2009
Tipo de documento:
Article