Risk assessment model for first-cycle chemotherapy-induced neutropenia in patients with solid tumours.
Eur J Cancer Care (Engl)
; 19(5): 648-55, 2010 Sep.
Article
em En
| MEDLINE
| ID: mdl-20088918
ABSTRACT
Chemotherapy-induced neutropenia, the major dose-limiting toxicity of chemotherapy, is directly associated with concomitant morbidity, mortality and health-care costs. The use of prophylactic granulocyte colony-stimulating factors may reduce the incidence and duration of chemotherapy-induced neutropenia, and is recommended in high-risk patients. The objective of this study was to develop a model to predict first-cycle chemotherapy-induced neutropenia (defined as neutropenia grade>or=3, with or without body temperature>or=38 degrees C) in patients with solid tumours. A total of 1194 patients [56% women; mean age 58+/-12 years; 94% Eastern Cooperative Oncology Group (ECOG) status
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias
/
Neutropenia
/
Neutrófilos
Tipo de estudo:
Clinical_trials
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Aged
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Aged80
/
Female
/
Humans
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Male
/
Middle aged
País/Região como assunto:
Europa
Idioma:
En
Revista:
Eur J Cancer Care (Engl)
Assunto da revista:
ENFERMAGEM
/
NEOPLASIAS
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Espanha