Drug treatments in a neonatal setting: focus on the off-label use in the first month of life.
Pharm World Sci
; 32(2): 120-4, 2010 Apr.
Article
em En
| MEDLINE
| ID: mdl-20140705
ABSTRACT
OBJECTIVE:
The purpose of this work was to analyse drugs prescribed in the first month of life among a group of newborns admitted to the Neonatal Intensive Care Unit and Neonatal Pathology of Cagliari University Hospital.METHOD:
This pilot study was prospectively conducted during a 1-month period and involved all newborns admitted to our hospital that received a pharmacotherapy. After obtaining written parental consent, data collected from each newborn included date of birth, sex, gestational age and weight. Also, diagnosis and information about each drug administered during the first month of life dose, frequency, route of administration, and indication for use was collected.RESULTS:
Among the 79 newborn infants admitted to our hospital during the study period, 38 received a pharmacotherapy and were enrolled in our study. A total of 88 treatments were given 41 (47%) followed the terms of the product license, 47 (53%) were used in an unlicensed or off-label manner.CONCLUSION:
Our results confirm this trend of drug use in the neonatological field and suggest the need to update information contained in the data sheets of medicines.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Unidades de Terapia Intensiva Neonatal
/
Uso Off-Label
Tipo de estudo:
Observational_studies
Limite:
Female
/
Humans
/
Male
/
Newborn
País/Região como assunto:
Europa
Idioma:
En
Revista:
Pharm World Sci
Assunto da revista:
FARMACIA
/
TERAPIA POR MEDICAMENTOS
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Itália