Synthesis, antibacterial and antifungal activities of some carbazole derivatives.
Bioorg Med Chem Lett
; 20(6): 1881-4, 2010 Mar 15.
Article
em En
| MEDLINE
| ID: mdl-20176480
ABSTRACT
A series of N-substituted carbazole derivatives were synthesized and evaluated for antibacterial and antifungal activities against Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA), Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Bacillus proteus, Candida albicans and Aspergillus fumigatus by two fold serial dilution technique. Some of the synthesized compounds displayed comparable or even better antibacterial and antifungal activities than reference drugs fluconazole, chloramphenicol and norfloxacin against tested strains.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Carbazóis
/
Antibacterianos
/
Antifúngicos
Idioma:
En
Revista:
Bioorg Med Chem Lett
Assunto da revista:
BIOQUIMICA
/
QUIMICA
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
China