Accuracy of Doppler-derived pulmonary artery hypertension to predict heart failure with normal ejection fraction.
Int J Cardiol
; 145(2): 370-372, 2010 Nov 19.
Article
em En
| MEDLINE
| ID: mdl-20207431
ABSTRACT
Recent advances have highlighted the clinical relevance of pulmonary artery hypertension in terms of diagnosis and prognosis in heart failure with normal ejection fraction. We addressed the usefulness of Doppler-derived pulmonary artery systolic pressure to predict heart failure with normal ejection fraction in stable patients with exertional dyspnea. 25 patients referred for clinically indicated catheterism with evidence of heart failure according to the European diagnostic flowchart on "how to diagnose heart failure with normal ejection fraction" and 12 controls referred for clinically indicated catheterism without this condition according to the diagnostic flowchart on "how to exclude heart failure with normal ejection fraction" were included. None of the patients presented with Doppler-derived pulmonary vascular resistance >2.5 WU. By logistic regression analysis, pulmonary artery systolic pressure predicted heart failure with normal ejection fraction (p=0.006), with an optimal cut-off value of 35 mmHg (area under the ROC curve of 0.80 [0.64-0.92], p<0.001; sensitivity 76%, specificity 75%). Positive and negative predictive values were 93 and 50% for the cut-off value of 40 mmHg. Doppler-derived pulmonary artery hypertension is a landmark of heart failure with normal ejection fraction in patients without severely increased pulmonary vascular resistance and deserves further attention in upcoming international recommendations.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Volume Sistólico
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Ecocardiografia Doppler
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Insuficiência Cardíaca
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Hipertensão Pulmonar
Tipo de estudo:
Guideline
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Prognostic_studies
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Risk_factors_studies
Limite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Int J Cardiol
Ano de publicação:
2010
Tipo de documento:
Article