Synthesis of notoamide J: a potentially pivotal intermediate in the biosynthesis of several prenylated indole alkaloids.
J Org Chem
; 75(9): 2785-9, 2010 May 07.
Article
em En
| MEDLINE
| ID: mdl-20359229
ABSTRACT
An efficient total synthesis of notoamide J, a new prenylated indole alkaloid and potential biosynthetic precursor, is described herein. Starting from L-proline and a substituted tryptophan derivative, this synthesis also employs an oxidation and pinacol rearrangement for the formation of the oxindole in the final step.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Alcaloides Indólicos
Idioma:
En
Revista:
J Org Chem
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Estados Unidos