Wiring nanoscale biosensors with piezoelectric nanomechanical resonators.
Nano Lett
; 10(5): 1769-73, 2010 May 12.
Article
em En
| MEDLINE
| ID: mdl-20380440
ABSTRACT
Nanoscale integrated circuits and sensors will require methods for unobtrusive interconnection with the macroscopic world to fully realize their potential. We report on a nanoelectromechanical system that may present a solution to the wiring problem by enabling information from multisite sensors to be multiplexed onto a single output line. The basis for this method is a mechanical Fourier transform mediated by piezoelectrically coupled nanoscale resonators. Our technique allows sensitive, linear, and real-time measurement of electrical potentials from conceivably any voltage-sensitive device. With this method, we demonstrate the direct transduction of neuronal action potentials from an extracellular microelectrode. This approach to wiring nanoscale devices could lead to minimally invasive implantable sensors with thousands of channels for in vivo neuronal recording, medical diagnostics, and electrochemical sensing.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Transdutores
/
Técnicas Biossensoriais
/
Condutometria
/
Nanotecnologia
/
Sistemas Microeletromecânicos
Idioma:
En
Revista:
Nano Lett
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Estados Unidos