Differences among pollen-allergic patients with and without plant food allergy.
Int Arch Allergy Immunol
; 153(2): 182-92, 2010.
Article
em En
| MEDLINE
| ID: mdl-20413986
ABSTRACT
BACKGROUND:
A considerable number of pollen-allergic patients develops allergy to plant foods, which has been attributed to cross-reactivity between food and pollen allergens. The aim of this study was to analyze the differences among pollen-allergic patients with and without plant food allergy.METHODS:
Eight hundred and six patients were recruited from 8 different hospitals. Each clinical research group included 100 patients (50 plant food-allergic patients and 50 pollen-allergic patients). Diagnosis of pollen allergy was based on typical case history of pollen allergy and positive skin prick tests. Diagnosis of plant-food allergy was based on clear history of plant-food allergy, skin prick tests and/or plant-food challenge tests. A panel of 28 purified allergens from pollens and/or plant foods was used to quantify specific IgE (ADVIA-Centaur® platform).RESULTS:
Six hundred and sixty eight patients (83%) of the 806 evaluated had pollen allergy 396 patients with pollen allergy alone and 272 patients with associated food and pollen allergies. A comparison of both groups showed a statistically significant increase in the food and pollen allergy subgroup in frequency of (1) asthma (47 vs. 59%; p < 0.001); (2) positive skin test results to several pollens Plantago, Platanus, Artemisia, Betula, Parietaria and Salsola (p < 0.001); (3) sensitization to purified allergens Pru p 3, profilin, Pla a 1 - Pla a 2, Sal k 1, PR-10 proteins and Len c 1.CONCLUSION:
Results showed relevant and significant differences between both groups of pollen-allergic patients depending on whether or not they suffered from plant-derived food allergy.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Plantas Comestíveis
/
Rinite Alérgica Sazonal
/
Hipersensibilidade Alimentar
Limite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Int Arch Allergy Immunol
Assunto da revista:
ALERGIA E IMUNOLOGIA
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Espanha