Pyridine-based heterocycles. Synthesis of new pyrido [4',3':4,5]thieno[2,3-d]pyrimidines and related heterocycles.
Molecules
; 15(4): 2651-66, 2010 Apr 12.
Article
em En
| MEDLINE
| ID: mdl-20428071
ABSTRACT
The synthesis of the title compounds was achieved using ethyl 2-amino-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate (1) as starting material. The reaction of the amino ester 1 with phenylisothiocyanate in boiling ethanol afforded the thiourea derivative 5. The cyclization reactions of 5 under different reaction conditions led to different pyridothienopyrimidine derivatives. Other reactions of the latter derivatives leading to pyrido[4',3'4,5]thieno[2,3-d]triazolo[1,5-a]pyrimidines are also presented.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Piridinas
/
Pirimidinas
/
Compostos Heterocíclicos
Idioma:
En
Revista:
Molecules
Assunto da revista:
BIOLOGIA
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Egito