Profound reduction of invariant natural killer T cells in the peripheral blood of a patient with interleukin-1 receptor-associated kinase 4 deficiency.
Immunol Lett
; 132(1-2): 86-9, 2010 Aug 16.
Article
em En
| MEDLINE
| ID: mdl-20441778
ABSTRACT
We previously described a patient with a history of frequent life-threatening pneumonias, infections with bacterial pathogens, interleukin 1 receptor-associated kinase 4 deficiency, and failure to maintain antibody titers to polysaccharide antigens or to a neoantigen bacteriophage. In the present study, we show that the patient's peripheral blood mononuclear cells have a profound deficiency of invariant natural killer T cells.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Quinases Associadas a Receptores de Interleucina-1
/
Células T Matadoras Naturais
/
Síndromes de Imunodeficiência
Tipo de estudo:
Risk_factors_studies
Limite:
Child, preschool
/
Female
/
Humans
Idioma:
En
Revista:
Immunol Lett
Ano de publicação:
2010
Tipo de documento:
Article