Psychiatric features in children with genetic syndromes: toward functional phenotypes.
Child Adolesc Psychiatr Clin N Am
; 19(2): 229-61, viii, 2010 Apr.
Article
em En
| MEDLINE
| ID: mdl-20478498
ABSTRACT
Neurodevelopmental disorders with identified genetic etiologies present a unique opportunity to study gene-brain-behavior connections in child psychiatry. Parsing complex human behavior into dissociable components is facilitated by examining a relatively homogenous genetic population. As children with developmental delay carry a greater burden of mental illness than the general population, familiarity with the most common genetic disorders will serve practitioners seeing a general child population. In this article basic genetic testing and 11 of the most common genetic disorders are reviewed, including the evidence base for treatment. Based on their training in child development, family systems, and multimodal treatment, child psychiatrists are well positioned to integrate cognitive, behavioral, social, psychiatric, and physical phenotypes, with a focus on functional impairment.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Fenótipo
/
Síndrome de Rett
/
Síndrome de Down
/
Transtornos Mentais
Tipo de estudo:
Diagnostic_studies
Limite:
Child
/
Humans
Idioma:
En
Revista:
Child Adolesc Psychiatr Clin N Am
Assunto da revista:
PEDIATRIA
/
PSIQUIATRIA
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Estados Unidos