Oral contraceptives and breast cancer: a French case-control study.
Int J Epidemiol
; 20(1): 32-8, 1991 Mar.
Article
em En
| MEDLINE
| ID: mdl-2066241
ABSTRACT
PIP: The relationship between the risk of breast cancer and oral contraceptive (OC) use was investigated in a case-control study conducted in France between 1983-87 in 5 public hospitals. Some 464 cases ages 25-56 years and 542 matched controls were interviewed about their history of OC use. Results are provided for the entire population and for the subgroups of 358 and 379 premenopausal cases and controls. The multivariate relative risk estimate, for ever-use, was 1.5 (p0.01) in the entire group as well as in the premenopausal subgroup (p0.02). However, there was no evidence that the effect varied appreciably according to the duration of use, age at 1st use, use prior to 1st fullterm pregnancy, and time since 1st or last use. The risk was not altered for any particular OC brand. The authors conclude that because of the widespread attention given to the relationship between OC use and breast cancer, information bias might be responsible for a part of the excess of risk observed among OC ever-users.
Palavras-chave
Bias; Biology; Breast Cancer; Cancer; Contraception; Contraceptive Methods; Control Groups; Data Analysis; Data Collection; Demographic Factors; Developed Countries; Diseases; Error Sources; Europe; Family Planning; France; Measurement; Mediterranean Countries; Neoplasms; Oral Contraceptives; Population; Population Characteristics; Research Methodology; Risk Factors; Statistical Regression; Western Europe
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Mama
/
Anticoncepcionais Orais
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Middle aged
País/Região como assunto:
Europa
Idioma:
En
Revista:
Int J Epidemiol
Ano de publicação:
1991
Tipo de documento:
Article
País de afiliação:
França