Multi-projection fluorescence optical tomography using a handheld-probe-based optical imager: phantom studies.
Appl Opt
; 49(23): 4343-54, 2010 Aug 10.
Article
em En
| MEDLINE
| ID: mdl-20697435
ABSTRACT
A handheld-probe-based optical imager has recently been developed toward three-dimensional tomography. In this study, the improvement of target depth recovery was demonstrated using a multi-projection technique on large slab phantoms using 0.45 cc fluorescing target(s) (with 10 contrast ratio) of 1.5 to 2.5 cm deep. Tomographic results using single- and multi- (here dual) projection measurements (with and without a priori information of target location) were compared. In all experimental cases, the use of multi-projection measurements along with a priori information recovered target depth and location closer to their true values, demonstrating its applicability for clinical translation.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doenças Mamárias
/
Imagens de Fantasmas
/
Tomografia Óptica
Limite:
Female
/
Humans
Idioma:
En
Revista:
Appl Opt
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Estados Unidos