The ethics of using transgenic non-human primates to study what makes us human.
Nat Rev Genet
; 11(9): 658-62, 2010 09.
Article
em En
| MEDLINE
| ID: mdl-20717156
ABSTRACT
A flood of comparative genomic data is resulting in the identification of human lineage-specific (HLS) sequences. As apes are our closest evolutionary relatives, transgenic introduction of HLS sequences into these species has the greatest potential to produce 'humanized' phenotypes and also to illuminate the functions of these sequences. We argue that such transgenic apes would also be more likely than other species to experience harm from such research, which renders such studies ethically unacceptable in apes and justifies regulatory barriers between these species and other non-human primates for HLS transgenic research.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Primatas
/
Técnicas Genéticas
/
Pesquisa Biomédica
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Nat Rev Genet
Assunto da revista:
GENETICA
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Estados Unidos