Demyelinating symmetric motor polyneuropathy with high titers of anti-GM1 antibodies.
Muscle Nerve
; 42(4): 604-8, 2010 Oct.
Article
em En
| MEDLINE
| ID: mdl-20730877
ABSTRACT
High titers of anti-GM1 ganglioside antibodies have been associated with multifocal motor neuropathy, a chronic asymmetric and exclusively motor disorder. We describe a patient with a progressive selective motor but symmetric polyneuropathy, followed over 5 years, with markedly elevated titers of anti-GM1 antibodies. The electrophysiological changes suggestive of motor demyelination were widespread, beyond conduction block alone, and involved contiguous nerve segments with complete sparing of sensory conduction. Progressive, predominantly motor, symmetric, demyelinating polyneuropathy may be an unusual relative of multifocal motor neuropathy, associated with anti-GM1 antibodies.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Polineuropatias
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Anticorpos Anti-Idiotípicos
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Doenças Desmielinizantes
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Gangliosídeo G(M1)
Limite:
Adult
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Humans
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Male
Idioma:
En
Revista:
Muscle Nerve
Ano de publicação:
2010
Tipo de documento:
Article