Differentiation of lesions caused by mycotoxin T-2 from autolytic morphologic change in CD-1 mice.
J Comp Pathol
; 103(4): 379-85, 1990 Nov.
Article
em En
| MEDLINE
| ID: mdl-2079553
ABSTRACT
Experiments with topically applied T-2 trichothecene mycotoxin were undertaken to determine whether lesions caused by this toxin could be differentiated from autolysis. Two pathologists, who had previously seen lesions caused by T-2 toxin, graded lesions without knowledge of treatment group and stated whether the animal had received the toxin or not. Both pathologists differentiated T-2 toxin-treated mice up to 6 h post-mortem. Failure to distinguish between treated and control mice resulted in false-negative diagnoses only. It was concluded that the diagnosis of trichothecene mycotoxicosis would probably be missed more than 6 h post-mortem.
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Base de dados:
MEDLINE
Assunto principal:
Autólise
/
Toxina T-2
/
Micotoxicose
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Animals
Idioma:
En
Revista:
J Comp Pathol
Ano de publicação:
1990
Tipo de documento:
Article
País de afiliação:
Canadá