Men with hyperferritinemia and diabetes in the Mediterranean area do not have a higher iron overload than those without diabetes.
Diabetes Res Clin Pract
; 91(2): e33-6, 2011 Feb.
Article
em En
| MEDLINE
| ID: mdl-21055836
ABSTRACT
AIM:
To assess the role of iron overload in type 2 diabetic men with hyperferritinemia.METHODS:
150 men were recruited from a genetic screening programme for hereditary hemocromatosis (HH) and were tested for type 2 diabetes, other components of the metabolic syndrome, beta cell function (BCF), insulin sensitivity, high-sensitivity C-reactive protein and iron overload.RESULTS:
Fifty-one men had type 2 diabetes. They were older (p=0.017) and 99 had lower BCF (p<0.001) than non-diabetic men. None of the iron overload indexes was associated with diabetes.CONCLUSIONS:
Our findings dispute a role of iron overload in the pathogenesis of type 2 diabetes.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Sobrecarga de Ferro
/
Diabetes Mellitus Tipo 2
/
Ferritinas
Limite:
Aged
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Diabetes Res Clin Pract
Assunto da revista:
ENDOCRINOLOGIA
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Espanha