Oxidation of α-oxo-oximes to nitrile oxides with hypervalent iodine reagents.
J Org Chem
; 76(2): 728-31, 2011 Jan 21.
Article
em En
| MEDLINE
| ID: mdl-21175144
ABSTRACT
Upon reaction with PhI(OAc)(2), α-oxo-aldoximes are oxidized to α-oxo-nitrile oxides, while α-oxo-ketoximes are converted into nitrile oxides via the oxidative cleavage of the carbonyl-imino σ bond. The nitrile oxides thus formed were trapped with norbornene or styrene in good yield. α,α'-Dioxo-ketoximes react less efficiently.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Óxidos
/
Oximas
/
Iodo
/
Nitrilas
Idioma:
En
Revista:
J Org Chem
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Canadá