Differentiation of avian infectious bronchitis virus isolates by thermal sensitivity.
Avian Dis
; 22(3): 440-50, 1978.
Article
em En
| MEDLINE
| ID: mdl-212002
ABSTRACT
Six isolates of avian infectious bronchitis virus (IBV) at different passage levels in the chicken embryo were tested for sensitivity at 56 C, with the following results:
1) isolates differed in thermal sensitivity; 2) virus was inactivated in a first-order exponential-kinetics 2-component fashion indicative of a heterogeneous population with a preponderance, 98% or more, of thermal-sensitive (S) virions over thermal-resistant (R) virons; 3) R virions 2-component populations were inactivated; 4) recovered R virions could be maintained in continuous passage in the chicken embryo as a one-component population by the limiting-dilution technique, although there was a progressive parallel increase in thermal sensitivity associated directly with the continuous passage; 5) growth curves of isolated one-component populations of R virions were quantitatively and in time sequence similar to curves of 2-component populations of continuous-passage virus.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Temperatura
/
Vírus da Bronquite Infecciosa
/
Coronaviridae
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
Idioma:
En
Revista:
Avian Dis
Ano de publicação:
1978
Tipo de documento:
Article