Room temperature aryl trifluoromethylation via copper-mediated oxidative cross-coupling.
J Org Chem
; 76(4): 1174-6, 2011 Feb 18.
Article
em En
| MEDLINE
| ID: mdl-21235259
ABSTRACT
A method for the room temperature copper-mediated trifluoromethylation of aryl and heteroaryl boronic acids has been developed. This protocol is amenable to normal benchtop setup and reactions typically require only 1-4 h. Proceeding under mild conditions, the method tolerates a range of functional groups, allowing access to a variety of trifluoromethylarenes.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ácidos Borônicos
/
Cobre
/
Hidrocarbonetos Fluorados
Idioma:
En
Revista:
J Org Chem
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Estados Unidos