[Inhibitory effect of TBN on platelet aggregation in rabbit].
Zhong Yao Cai
; 33(9): 1450-3, 2010 Sep.
Article
em Zh
| MEDLINE
| ID: mdl-21243778
ABSTRACT
OBJECTIVE:
To investigate the inhibitory effect of TBN on rabbit platelet aggregation in vitro and in vivo, and compare with tetramethylpyrazine (TMP).METHODS:
To seek out the maximum of platelet aggregation (expressed in percentage) within 5 minutes which was induced by ADP, PAF and AA according to the Born turbidimetric method with a Platelet-Aggregometer.RESULTS:
TBN significantly inhibited platelet aggregation induced by ADP, PAF and AA both in vitro and in vivo. TBN was more active than TMP.CONCLUSION:
TBN has significant activity inhibiting platelet aggregation induced by ADP, PAF and AA in vitro and in vivo.
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Base de dados:
MEDLINE
Assunto principal:
Pirazinas
/
Medicamentos de Ervas Chinesas
/
Inibidores da Agregação Plaquetária
/
Agregação Plaquetária
Limite:
Animals
Idioma:
Zh
Revista:
Zhong Yao Cai
Assunto da revista:
TERAPIAS COMPLEMENTARES
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
China