Evaluation of dual flow counter-current chromatography and intermittent counter-current extraction.
J Chromatogr A
; 1218(36): 6102-6, 2011 Sep 09.
Article
em En
| MEDLINE
| ID: mdl-21397905
ABSTRACT
The aim of this research is to compare two continuous extraction technologies, intermittent counter-current extraction (ICcE) and dual flow counter-current chromatography (DFCCC), in terms of loading and throughput using the GUESSmix, and show the advantages and disadvantages of the two methods. A model sample containing caffeine, vanillin, naringenin and carvone, with a total load of 11.2 g, was employed with a hexane-ethyl acetate-methanol-water (2323) phase system to evaluate an ICcE method on a preparative (912 ml coil volume) DE-Midi instrument. While DFCCC was carried out on a specially designed preparative (561 ml coil volume) bobbin installed in a similar Midi instrument case. While similar throughputs of 7.8 g/h and 6.9 g/h were achieved for the ICcE and DFCCC methods respectively, ICcE was demonstrated to have a number of advantages over DFCCC.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Benzaldeídos
/
Cafeína
/
Distribuição Contracorrente
/
Monoterpenos
/
Flavanonas
Tipo de estudo:
Evaluation_studies
Idioma:
En
Revista:
J Chromatogr A
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Reino Unido