Impulse control disorders in Chinese Parkinson's disease patients: the effect of ergot derived dopamine agonist.
Parkinsonism Relat Disord
; 17(8): 635-7, 2011 Sep.
Article
em En
| MEDLINE
| ID: mdl-21705258
ABSTRACT
OBJECTIVE:
We studied the prevalence and related risk factors of impulse control disorders in Chinese Parkinson's disease patients.METHOD:
We screened all non-demented Parkinson's disease patients attending our Parkinson's disease clinic from August 2009 to March 2010. The clinical characteristics of patients with impulse control disorders and those without were compared.RESULTS:
Of the 213 PD subjects screened, 15 (7.0%) with impulse control disorders were identified. Fourteen of these subjects were on both a dopamine agonist and Levodopa, and one was on Levodopa alone. Of the fourteen subjects on both a dopamine agonist and Levodopa, eleven were on bromocriptine and Levodopa; 10.5% of the subjects exposed to bromocriptine had impulse control disorder. Upon multivariate analysis, dose of dopamine agonist used, young age at onset of Parkinson's disease and a history of anxiety or depression were independent predictors for developing impulse control disorders.CONCLUSIONS:
7% of our Chinese PD subjects had impulse control disorders. When young Parkinson's disease patients with a history of anxiety or depression are treated with high dose of DA, they are at risk of developing impulse control disorders.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doença de Parkinson
/
Bromocriptina
/
Levodopa
/
Agonistas de Dopamina
/
Povo Asiático
/
Transtornos Disruptivos, de Controle do Impulso e da Conduta
Tipo de estudo:
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Asia
Idioma:
En
Revista:
Parkinsonism Relat Disord
Assunto da revista:
NEUROLOGIA
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
China