New Nanomedicine Approaches Using Gold-thioguanine Nanoconjugates as Metallo-ligands.
Inorganica Chim Acta
; 372(1): 333-339, 2011 Jun 15.
Article
em En
| MEDLINE
| ID: mdl-21709763
ABSTRACT
Gold-thioguanine nanoconjugates (AuNP-TG) of size 3-4 nm were synthesized and the ratio between gold and 6-Thioguanine (TG) was estimated as ~11.5 using a cyanide digestion method and confirmed by flame atomic absorption spectroscopic analysis. AuNP-TG constructs showed high in vitro stability under different pH conditions and biologically relevant solutions for a period of 24 hours. Reaction of AuNP-TG with europium or platinum salts resulted in the formation of organized self-assembled metallo-networks.
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Base de dados:
MEDLINE
Idioma:
En
Revista:
Inorganica Chim Acta
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Estados Unidos