Moderators of cancer-related distress and worry after a pancreatic cancer genetic counseling and screening intervention.
Psychooncology
; 21(12): 1324-30, 2012 Dec.
Article
em En
| MEDLINE
| ID: mdl-21774034
ABSTRACT
OBJECTIVES:
Although the hereditary breast and ovarian cancer literature has demonstrated short-term gains in psychological adjustment following genetic counseling, there has been limited research examining long-term outcomes and moderators. Moreover, there has been minimal research into the psychological effects of this intervention in populations at high risk for pancreatic cancer. This study examines the long-term effects of pancreatic cancer screening and genetic counseling on cancer-related distress and cancer worry in a high-risk population at 1-year follow-up. Additionally, this study explores potential moderators of the effectiveness of this intervention.METHODS:
One hundred twenty-nine participants with familial pancreatic cancer or with the BRCA2 gene mutation completed a baseline questionnaire prior to their first pancreatic cancer screening and genetic counseling session. Participants also completed questionnaires at 3- and 12-month follow-up.RESULTS:
Cancer-related intrusive thoughts decreased significantly over time, whereas cancer-related worry decreased at 3 months and showed a small but significant increase at 1 year. Age and baseline distress exhibited moderator effects. Younger individuals showed a significant decrease in cancer-related intrusive thoughts, cancer-related avoidant thoughts, and cancer worry. Additionally, individuals with greater baseline distress showed a significant decrease in cancer-related intrusive thoughts over time.CONCLUSIONS:
Analysis of the long-term effects of pancreatic cancer screening and genetic testing reveal psychological gains that are maintained at 1-year follow-up. This intervention is particularly effective for younger participants and individuals with greater baseline distress.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ansiedade
/
Neoplasias Pancreáticas
/
Adenocarcinoma
/
Testes Genéticos
/
Detecção Precoce de Câncer
/
Aconselhamento Genético
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Qualitative_research
/
Risk_factors_studies
/
Screening_studies
Limite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Psychooncology
Assunto da revista:
NEOPLASIAS
/
PSICOLOGIA
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Canadá