[A new fructosamine test--as a routine parameter in the control of diabetes]. / Neuer Fructosamin-Test--als Routineparameter in der Diabeteskontrolle.
Wien Klin Wochenschr Suppl
; 180: 5-10, 1990.
Article
em De
| MEDLINE
| ID: mdl-2181784
ABSTRACT
Measurement of protein glycation (fructosamine) has become an accepted tool in diabetes diagnostics. Among different methods available, the serum fructosamine test published by Johnson and Baker in 1983 has gained wide acceptance due to a simple and easily automated assay procedure providing clinically meaningful results. A recent modification of the Nitroblue Tetrazolium (NBT) reagent, improved by addition of tensides and uricase, exhibits lower interference by lipaemia and urate. It is also less affected by the sample matrix and yields results closer to the physiological range of glycated proteins. Furthermore, a completely new standardization protocol was used in the preparation of calibration material. The new colorimetric method for the determination of fructosamine was evaluated in 12 European clinical laboratories.
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Base de dados:
MEDLINE
Assunto principal:
Glicoproteínas
/
Diabetes Mellitus
/
Hexosaminas
Tipo de estudo:
Guideline
/
Observational_studies
/
Prognostic_studies
Limite:
Humans
Idioma:
De
Revista:
Wien Klin Wochenschr Suppl
Ano de publicação:
1990
Tipo de documento:
Article