The growing impact of pediatric pharmaceutical poisoning.
J Pediatr
; 160(2): 265-270.e1, 2012 Feb.
Article
em En
| MEDLINE
| ID: mdl-21920539
ABSTRACT
OBJECTIVE:
To understand which medications, under which circumstances, are responsible for the noted increase in pediatric medication poisonings, resource use, and morbidity. STUDYDESIGN:
Patient records from 2001-2008 were obtained from the National Poison Data System of the American Association of Poison Control Centers for children aged ≤5 years evaluated in a health care facility following exposure to a potentially toxic dose of a pharmaceutical agent. Pharmaceutical agents were classified as over-the-counter or prescription and by functional category. Exposures were classified as child self-ingested the medication or as therapeutic error. For the 8-year period, emergency visits, admissions, significant injuries, and trends in these events were calculated for each substance category.RESULTS:
We evaluated 453 559 children for ingestion of a single pharmaceutical product. Child self-exposure was responsible for 95% of visits. Child self-exposure to prescription products dominated the health care impact with 248 023 of the visits (55%), 41 847 admissions (76%), and 18 191 significant injuries (71%). The greatest resource use and morbidity followed self-ingestion of prescription products, particularly opioids, sedative-hypnotics, and cardiovascular agents.CONCLUSIONS:
Prevention efforts have proved to be inadequate in the face of rising availability of prescription medications, particularly more dangerous medications.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Medicamentos sob Prescrição
/
Hospitalização
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Newborn
País/Região como assunto:
America do norte
Idioma:
En
Revista:
J Pediatr
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Estados Unidos