False-positive urine phencyclidine immunoassay screen result caused by interference by tramadol and its metabolites.
Ann Emerg Med
; 59(6): 545-7, 2012 Jun.
Article
em En
| MEDLINE
| ID: mdl-21924518
ABSTRACT
Phencyclidine is one of the drugs of abuse included in qualitative urine drug screens that are frequently ordered in the emergency department despite concerns about specificity and clinical utility. Many drugs have been described to cause false-positive results for phencyclidine. We present 2 cases of false-positive phencyclidine qualitative urine drug screen results in patients with seizures from tramadol misuse or abuse. The involvement of tramadol and its active metabolite, N-desmethyltramadol, was confirmed by in vitro testing. These cases illustrate that tramadol and its metabolites can trigger a false-positive phencyclidine urine drug screen result in nonfatal cases and highlight the lack of specificity of the phencyclidine qualitative urine drug screen.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Fenciclidina
/
Tramadol
Tipo de estudo:
Diagnostic_studies
/
Qualitative_research
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Ann Emerg Med
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Estados Unidos