Relationship between macular ganglion cell complex parameters and visual field parameters after tumor resection in chiasmal compression.
Jpn J Ophthalmol
; 56(1): 68-75, 2012 Jan.
Article
em En
| MEDLINE
| ID: mdl-21975828
ABSTRACT
PURPOSE:
To evaluate the relationship between macular ganglion cell complex (GCC) parameters and visual field (VF) parameters in chiasmal compression and the potential for GCC parameters in order to predict the short-term postsurgical VF.METHODS:
Twenty-three eyes of 12 patients with chiasmal compression and 33 control eyes were studied. All patients underwent transsphenoidal tumor resection. Before surgery a 3D scan of the macula was taken using spectral-domain optical coherence tomography. All patients underwent Humphrey 24-2 VF testing after surgery. Spearman's rank correlation coefficients were used to evaluate the relationship between the GCC parameters and VF parameters [mean deviation (MD), pattern standard deviation]. Coefficients of determination (R2) were calculated using linear regression.RESULTS:
Average thickness in the patients was significantly thinner than that of controls. Average thickness, global loss volume and focal loss volume (FLV) significantly correlated with the MD. We observed the greatest R2 between FLV and MD.CONCLUSIONS:
Examining the macular GCC was useful for evaluating structural damage in patients with chiasmal compression. Preoperative GCC parameters, especially FLV, may be useful in predicting visual function following surgical decompression of chiasmal compression.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Quiasma Óptico
/
Neoplasias Hipofisárias
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Células Ganglionares da Retina
/
Campos Visuais
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Síndromes de Compressão Nervosa
/
Fibras Nervosas
Tipo de estudo:
Etiology_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Jpn J Ophthalmol
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Japão