Prevalence of human leukocyte antigen HLA-B*57:01 in HIV-infected subjects in the Czech Republic.

Jilich, David; Vraná, Milena; Snopková, Svatava; Sedlácek, Dalibor; Kapla, Jaroslav; Rozsypal, Hanus; Kolcáková, Jitka; Olbrechtová, Lenka; Zjevíková, Alena; Jerhotová, Zdenka; Malý, Marek; Stanková, Marie; Machala, Ladislav

Jilich, David; Vraná, Milena; Snopková, Svatava; Sedlácek, Dalibor; Kapla, Jaroslav; Rozsypal, Hanus; Kolcáková, Jitka; Olbrechtová, Lenka; Zjevíková, Alena; Jerhotová, Zdenka; Malý, Marek; Stanková, Marie; Machala, Ladislav.

Afiliação

Jilich D; Department of Infectious and Tropical Diseases, First Faculty of Medicine, Charles University in Prague, Czech Republic.

Cent Eur J Public Health ; 19(3): 128-30, 2011 Sep.

Article em En | MEDLINE | ID: mdl-22026283

ABSTRACT

ABSTRACT

The HLA-B*5701 allele is associated with a hypersensitivity reaction to abacavir, and its prevalence varies in different populations. The aim of the study was to investigate HLA-B*5701 prevalence in the Czech HIV-infected population. HLA-B*5701 prevalence in our cohort was 5.33%, which is similar to the situation in other Central European countries.

Assuntos

Hipersensibilidade a Drogas/epidemiologia; Antígenos HLA-B; Fármacos Anti-HIV/efeitos adversos; Estudos Transversais; República Tcheca/epidemiologia; Didesoxinucleosídeos/efeitos adversos; Hipersensibilidade a Drogas/diagnóstico; Infecções por HIV/sangue; Infecções por HIV/tratamento farmacológico; Antígenos HLA-B/sangue; Humanos; Prevalência

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Base de dados: MEDLINE Assunto principal: Antígenos HLA-B / Hipersensibilidade a Drogas Tipo de estudo: Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Humans País/Região como assunto: Europa Idioma: En Revista: Cent Eur J Public Health Assunto da revista: EPIDEMIOLOGIA / SAUDE PUBLICA Ano de publicação: 2011 Tipo de documento: Article País de afiliação: República Tcheca

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