Ultrasound-guided sentinel node procedure for nonpalpable breast carcinoma.
Nucl Med Commun
; 33(1): 80-3, 2012 Jan.
Article
em En
| MEDLINE
| ID: mdl-22044865
ABSTRACT
PURPOSE:
Peritumoral and periareolar tracer injection techniques lead to different lymphatic drainage in sentinel lymph node biopsy procedures. In a prospective study, the visualization and identification rates of the ultrasound (US)-guided tracer injection technique for palpable and nonpalpable breast tumors were evaluated.METHODS:
In 1262 consecutive patients with cT1â2N0 breast cancer, sentinel lymph node biopsy was performed following peritumoral tracer injection. In the case of nonpalpable breast lesions, Tc-99m nanocolloid injections were given using a 7.5 MHz US probe. In the case of ultrasonographically nonvisible microcalcifications, the US-guided injection technique was wire guided.RESULTS:
In 331 patients with nonpalpable breast lesions (26.2%), the lymphoscintigraphic visualization and surgical retrieval rates of axillary sentinel lymph nodes (SLNs) were 98.5 and 99.4%, respectively. For internal mammary (IM) SLNs, these rates were 21.1 and 17.8%, respectively. These rates were similar in patients with palpable and nonpalpable tumors. Axillary metastases were detected in 38.7% of the patients with palpable tumors versus 16.5% of those with nonpalpable tumors (P<0.001), whereas IM metastases were found in 4.8 and 3.0% of patients, respectively (P=0.165).CONCLUSION:
In nonpalpable breast lesions, the US-guided injection technique is an accurate technique for SLN identification and retrieval. The substantial rates of IM metastases in both palpable and nonpalpable lesions favor a peritumoral tracer injection technique.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Mama
/
Neoplasias da Mama
/
Agregado de Albumina Marcado com Tecnécio Tc 99m
/
Compostos Radiofarmacêuticos
/
Biópsia de Linfonodo Sentinela
/
Linfonodos
Tipo de estudo:
Observational_studies
Limite:
Aged
/
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Nucl Med Commun
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Holanda