Influence of gestational age and reason for prior preterm birth on rates of recurrent preterm delivery.
Am J Obstet Gynecol
; 205(3): 275.e1-5, 2011 Sep.
Article
em En
| MEDLINE
| ID: mdl-22071063
OBJECTIVE: We sought to compare rates of recurrent spontaneous preterm birth (SPTB) in women receiving 17-α-hydroxyprogesterone caproate (17P) with prior SPTB due to preterm labor (PTL) vs preterm premature rupture of membranes (PPROM). STUDY DESIGN: Women with singleton gestation having 1 prior SPTB enrolled at 16-24.9 weeks' gestation for weekly outpatient 17P administration were identified from a database. Rates of recurrent SPTB were compared between those with prior SPTB due to PTL or PPROM overall and by gestational age at prior SPTB. RESULTS: Records from 2123 women were analyzed. The prior PTL group vs the prior PPROM group experienced higher rates of recurrent SPTB at <37 weeks (29.7% vs 22.9%, P = .004), <35 weeks (14.0% vs 9.1%, P = .004), and <32 weeks (5.9% vs 3.3%, P = .024), respectively. CONCLUSION: Reason and gestational age of prior SPTB influence the likelihood of recurrent SPTB in women receiving 17P prophylaxis.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Progestinas
/
Ruptura Prematura de Membranas Fetais
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Idade Gestacional
/
Nascimento Prematuro
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Hidroxiprogesteronas
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
Limite:
Adult
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Female
/
Humans
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Newborn
/
Pregnancy
Idioma:
En
Revista:
Am J Obstet Gynecol
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Estados Unidos